SSX2IP (synovial sarcoma, X breakpoint 2 interacting protein)
نویسندگان
چکیده
منابع مشابه
SSX 2 ( Synovial Sarcoma , X breakpoint 2 )
Description So far, two SSX2 protein isoforms (a and b) are known to exist. Their mRNAs correspond to SV1 (1466 bases) and SV3 (1322 bases) splice variants, respectively. The start codon for both isoforms is located in Exon 2. SSX2 isoform a is 233 amino acids (26.5 kD) and SSX2 isoform b 188 amino acids (21.6 kD). Of both isoforms, SSX2 isoform b is the most commonly seen and so far the best s...
متن کاملThe novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone
In differentiated human cells, primary cilia fulfill essential functions in converting mechanical or chemical stimuli into intracellular signals. Formation and maintenance of cilia require multiple functions associated with the centriole-derived basal body, from which axonemal microtubules grow and which assembles a gate to maintain the specific ciliary proteome. Here we characterize the functi...
متن کاملThe centriolar satellite protein SSX2IP promotes centrosome maturation
Meiotic maturation in vertebrate oocytes is an excellent model system for microtubule reorganization during M-phase spindle assembly. Here, we surveyed changes in the pattern of microtubule-interacting proteins upon Xenopus laevis oocyte maturation by quantitative proteomics. We identified the synovial sarcoma X breakpoint protein (SSX2IP) as a novel spindle protein. Using X. laevis egg extract...
متن کاملSynovial sarcoma
Key-words Disease name Definition/Diagnostic criteria Differential diagnosis Etiology Clinical description Diagnostic methods Prognostic factors Epidemiology Management Unresolved questions References
متن کاملsynovial cell sarcoma
ten cases of synovial cell sarcoma are reported. the youngest patient was a 2'a years old boy with synovial cell sarcoma of the knee and the oldest one was a man with synovial cell sarcoma of the elbow.
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2012
ISSN: 1768-3262
DOI: 10.4267/2042/47489